Articles-Health Sciences(ACP)
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Item Recent Advances in Predicting Protein Classification and Their Applications to Drug Development : Current Topics in Medicinal Chemistry,(Bentham Science, 2024-09-06) Xuan Xiao1,2,4,*, Wei-Zhong Lin1 and Kuo-Chen Chou3,4Item Recent progress of ferroptosis in cancers and drug discovery : Asian Journal of Pharmaceutical Sciences(Elsevier, 2024-09-06) Xiang Wang a,1 , Xinxin Renb,c,d,1 , Xu Line,1 , Qi Li a , Yingqiong Zhang a , Jun Deng a , Binxin Chena , Guoqing Rub,∗ , Ying Luo a,∗ , Nengming Lina,f,g,∗Item Treatment of inflammatory bowel disease with steroid-sparing medications is age-dependent – Results from a Danish nationwide cohort study, 2000–2018 : Alimentary Pharmacology & Therapeutics(Wiley, 2024-09-03) Rie Louise Møller Nordestgaard1,2 | Mads Damsgaard Wewer1,2 | Mikkel Malham2,3,4 | Vibeke WewerItem Clinical trial: An open-label, randomised trial of different re-start strategies after treatment withdrawal in HBeAg negative chronic hepatitis B : Alimentary Pharmacology & Therapeutics(Wiley, 2024-09-03) Asgeir Johannessen1,2,3 | Dag Henrik Reikvam2,3 | Soo Aleman 4 | Nega Berhe1,2,5 | Nina Weis 6,7 | Hailemichael Desalegn1,Item Systematic review: Patient-related, microbial, surgical, and histopathological risk factors for endoscopic post-operative recurrence in patients with Crohn's disease : Alimentary Pharmacology & Therapeutics(Wiley, 2024-09-03) Michiel T. J. Bak1 | Karlijn Demers2,3,4 | Nassim Hammoudi5 | Matthieu Allez5 | Mark S. Silverberg6Item Automated Poisson regression exposure–response analysis for binary outcomes with PoissonERM : CPT: Pharmacometrics & Systems Pharmacology(Wiley, 2024-09-03) Yuchen Wang1 | Luke Fostvedt2 | Jessica Wojciechowski3 | Donald Irby4 | Timothy NicholasItem Characterization of mavacamten pharmacokinetics in patients with hypertrophic cardiomyopathy to inform dose titration : CPT: Pharmacometrics & Systems Pharmacology(Wiley, 2024-09-03) Peter Chang1 | Vidya Perera 2,* | David H. Salinger1 | Samira Merali2 | Neelima Thanneer2 | Hyunmoon Back2 | Julie D. Seroogy et...al.Item Enhancing inclusivity in clinical trials: Model-informed drug development for pregnant individuals in the era of personalized medicine : CPT: Pharmacometrics & Systems Pharmacology(Wiley, 2024-09-03) André Dallmann1 | Peter L. Bonate2 | Janelle Burnham 3, * | Blessy George4 | Lynne Yao 5 | Jane Knöchel 6Item A stacking ensemble machine learning model for evaluating cardiac toxicity of drugs based on in silico biomarkers : CPT: Pharmacometrics & Systems Pharmacology(Wiley, 2024-09-03) Yunendah Nur Fuadah1,2 | Ali Ikhsanul Qauli1,3 | Muhammad Adnan Pramudito1 | Aroli Marcellinus1 | Ulfa Latifa Hanum1 | Ki Moo Lim1Item A fully automatic tool for development of population pharmacokinetic models : CPT Pharmacometrics & Systems Pharmacology(Wiley, 2024-09-03) Xiaomei Chen1 | Rikard Nordgren1 | Stella Belin1 | Alzahra Hamdan 1 | Shijun Wang 1 | Tianwu Yang. et....al.Item Development of a Multifaceted Program for Pharmacogenetics Adoption at an Academic Medical Center: Practical Considerations and Lessons Learned : Clinical Pharmacology and Therapeutics(Wiley, 2024-09-03) Emma M. Tillman1,† , Amy M. Breman2 , Jennelle C. Hodge2 , Christine A. McDonald1 , Reynold C. Ly et.....al.Item A Pooled Population Pharmacokinetic Study of Oral and Intravenous Administration of Clavulanic Acid in Neonates and Infants: Targeting Effective Beta- Lactamase Inhibition : Clinical Pharmacology and Therapeutics(Wiley, 2024-09-03) Stef Schouwenburg1,2,† , Fleur M. Keij3,4,† , Gerdien A. Tramper-Stranders3,4 , René F. Kornelisse3 , Irwin K. M. Reiss3,4 , Pieter A. J. G. de Cock 5,6 , Evelyn Dhont et....al.Item The Rare Disease Moonshot: Paradigms Shift, Translational Medicine, and Regulatory Science for the World’s Rarest Conditions : Clinical Pharmacology and Therapeutics(Wiley, 2024-09-03) Cécile Ollivier 1, * , Solange Corriol- Rohou 2 , Marta del Álamo3, Roseline Favresse 4, Johanna Kostenzer 5 , Mathieu Boudes6 et....al.Item Assessing Post-Marketing Requirements for Orphan Drugs: A Cross-Sectional Analysis of FDA and EMA Oversight : Clinical Pharmacology and Therapeutics(Wiley, 2024-09-03) Jae Hyeon Yu1,† , Sangwon Lee 2,3,† , Yoon Jung Kim 1, Won Young Kim 1, Min Jung Lee 1 and Yun Kim 1, *Item Comparison of disease-modifying anti-rheumatic drugs and hyperbaric oxygen therapy in the experimental model of rheumatoid arthritis in rats : Clinical and Experimental Pharmacology and Physiology(John Wiley & Sons,, 2024-09-03) Mohamad Hallak 1 | Ahmet Inal 2 | Mehmet Akif Baktir 3 | Ayhan Atasever 4Item The effect of severe renal impairment on the pharmacokinetics, safety and tolerability of mitiperstat : British Journal of Clinical Pharmacology(John Wiley & Sons,, 2024-09-03) Chandrali S. Bhattacharya 1 | Patricia Ely Pizzato 2 | Maria Heijer 3 | Mikael Sunnåker 4 | Julie Holden 5 | Monika Trebski 5 | Karin Nelander et....al.Item Factors affecting peripheral neuropathy induced by nanoparticle albumin-bound paclitaxel in patients with pancreatic cancer : British Journal of Clinical Pharmacology(John Wiley & Sons,, 2024-09-03) Minseo Kang 1 | Seunghyun Yoo 1 | Yeolmae Jung 1 | Hayun Lim1 | Myeong Hwan Lee 2 | Ji Kon Ryu2 | Jangik I. LeeItem Population pharmacokinetic/target engagement modelling of tozorakimab in healthy volunteers and patients with chronic obstructive pulmonary disease : British Journal of Clinical Pharmacology(John Wiley & Sons,, 2024-09-03) Muhammad Waqas Sadiq 1 | Hongtao Yu 2 | Magnus Åstrand 1 | Ian C. Scott 3 | Adam Williams 4 | Lisa Hewitt 5 | Nicholas White 4 | Helen Killick 3 | et....al.Item Pharmacokinetics and pharmacodynamics of PTC518, an oral huntingtin lowering splicing modifier: A first-in-human study : British Journal of Clinical Pharmacolog(John Wiley & Sons,, 2024-09-03) an Gao 1 | Anuradha Bhattacharyya 1 | Brian Beers 1 | Diksha Kaushik 1 | Amy-Lee Bredlau 1 | Allan Kristensen 1 | Khalid Abd-Elaziz 2 | Richard Grant 1 | Lee Golden 1 | Ronald KongItem Analysis of longitudinal patterns and predictors of medicine use in residential aged care using group-based trajectory modelling: The MEDTRAC-Polypharmacy longitudinal cohort study :(John Wiley & Sons,, 2024-09-03) Nasir Wabe | Rachel Urwin | Karla Seaman | Andrea Timothy | Magdalena Z. Raban | Johanna Westbrook : British Journal of Clinical Pharmacology